The software includes two programs that are simple to use, yet
giving the most demonstrative results, showing every cell in the
crypt of intestinal epithelium.
The main program, Cell Division in Crypt, performs computer
simulation of the processes of cell proliferation, cell movement
and growth in the crypt in accordance with the
spatial/topological requirements for cell division in this
particular tissue, as outlined in our Main page.
The accessory program, Crypt Builder, allows to build an
initial crypt configuration. It also allows to construct other
tissue models with different structures and cell arrangements and
then to test their proliferative capabilities in the main
program. The modeling of tissues presenting a particular interest
for individual researchers is possible, as long as the structure
remains essentially two-dimensional. However, folding the
two-dimensional structures, as we believe, can generate models of
the real tissues which, possibly, are just this - a folded sheet
of connected cells.
The functioning of both programs is described in Program Help.
Supported operating systems are Windows 98/ME/2000/XP.
We believe that this program can serve as an excellent tool for classroom demonstration in Cell Biology.
Cell Division in Crypt